Search Thermo Fisher Scientific
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ankyrin repeat and SOCS box protein 7; ankyrin repeat and SOCS box-containing 7; ankyrin repeat and SOCS box-containing protein 7; ASB-7
基因别名: AI449039; Asb-7; ASB7; D030055C23Rik
UniProt ID: (Human) Q9H672, (Mouse) Q91ZU0
Entrez Gene ID: (Human) 140460, (Mouse) 117589, (Rat) 365277