Search Thermo Fisher Scientific
ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acid sensing (proton gated) ion channel 3; acid sensing ion channel 3; acid-sensing (proton-gated) ion channel 3; Acid-sensing ion channel 3; Amiloride-sensitive cation channel 3; amiloride-sensitive cation channel 3, testis; ASIC3; Dorsal root ASIC; DRASIC; hASIC3; hTNaC1; modulatory subunit of ASIC2a; Neuronal amiloride-sensitive cation channel 3; proton gated cation channel DRASIC; proton-gated cation channel subunit; Testis sodium channel 1
基因别名: ACCN3; ASIC3; AW742291; DRASIC; SLNAC1; TNAC1
UniProt ID: (Human) Q9UHC3, (Mouse) Q6X1Y6, (Rat) O35240
Entrez Gene ID: (Human) 9311, (Mouse) 171209, (Rat) 286920
分子生物学功能:
ion channel