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产品信息
H00055252-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ASXL2 (AAH42999, 1 a.a. approximately 918 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.38 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKRTKCADID VETPDSILVN TNLRALINKH TFSVLPGDCQ QRLLLLLPEV DRQVGPDGLM KLNGSALNNE FFTSAAQGWK ERLSEGEFTP EMQVRIRQEI EKEKKVEPWK EQFFESYYGQ SSGLSLEDSK KLTASPSDPK VKKTPAEQPK SMPVSEASLI RIVPVVSQSE CKEEALQMSS PGRKEECESQ GEVQPNFSTS SEPLLSSALN THELSSILPI KCPKDEDLLE QKPVTSAEQE SEKNHLTTAS NYNKSESQES LVTSPSKPKS PGVEKPIVKP TAGAGPQETN MKEPLATLVD QSPESLKRKS SLTQEEAPVS WEKRPRVTEN RQHQQPFQVS PQPFLNRGDR IQVRKVPPLK IPVSRISPMP FHPSQVSPRA RFPVSITSPN RTGARTLADI KAKAQLVKAQ RAAAAAAAAA AAAASVGGTI PGPGPGGGQG PGEGGEGQTA RGGSPGSDRV SETGKGPTLE LAGTGSRGGT RELLPCGPET QPQSETKTTP SQAQPHSVSG AQLQQTPPVP PTPAVSGACT SVPSPVHIEK LDNEKLNPTR ATATVASVSH PQGPSSCRQE KAPSPTGFQL EDISTSQRFM LGFAGRRTSK PAMAGHYLLN ISTYGRGSES FRRTHSVNPE DRFCLSSPTE ALKMGYTDCK NATGESSSSK EDDTDEESTG DEQESVTVKE EPQVSQSAGK GDTSSGPHSR ETLSTSDCLA SKNVKAEIPL NEQTTLSKEN YLFTRGQTFD EKTLARDLIQ AAQKQMAHAV RGKAIRSSPE LFSSTVLPLP ADSPTHQPLL LPPLQTPKLY GSPTQIGPSY RGMINVSTSS DMDHNSAVPG SQVSSNVGDV MSFSVTVTTI PASQAMNPSS HGQTIPVQAF SEENSIEGTP SKCYCRLKAM IMCKGCGAFC HDDCIGPSKL CVSCLVVR
靶标信息
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: additional sex combs like 2; additional sex combs like transcriptional regulator 2; Additional sex combs-like protein 2; polycomb group protein ASXH2; Putative Polycomb group protein ASXL2
基因别名: ASXH2; ASXL2; KIAA1685
UniProt ID: (Human) Q76L83
Entrez Gene ID: (Human) 55252
