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Immunogen sequence: NVDRHVDLLE VAQETDGFSG SDLKEMCRDA ALLCVREYVN STSEESHDED EIRPVQQQDL HRAIEKMKKS KDAAFQ
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AAA+ ATPase Thorase; ATPase family AAA domain-containing protein 1; ATPase Thorase; FLJ14600; hATAD1; Outer mitochondrial transmembrane helix translocase; Thorase
基因别名: AFDC1; ATAD1; FNP001; THORASE
UniProt ID: (Human) Q6DKG1
Entrez Gene ID: (Human) 84896