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Immunogen sequence: MSWLFGINKG PKGEGAGPPP PLPPAQPGAE GGGDRGLGDR PAPKDKWSNF DPTGLERAAK AARELEHSRY AKDALNLAQM QEQTLQLEQQ SKLKEYEAAV EQLKSEQIRA QAEERRKTLS EETRQHQARA QYQDKLARQR YEDQLKQQQL LNEENLRKQE ESVQKQEAMR RATVEREMEL RHKNEMLRVE AEARARAKAE RENADIIREQ IRLKAAEHRQ TVLESIRTAG TLFGEGFRAF; Positive Samples: HeLa, Jurkat, MCF7, HepG2, Mouse liver, Mouse kidney, Mouse brain; Cellular Location: Mitochondrion inner membrane, Mitochondrion matrix, Single-pass membrane protein, mitochondrion nucleoid
ATAD3A is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AAA-ATPase TOB3; ATPase family AAA domain-containing protein 3; ATPase family AAA domain-containing protein 3A; RP5-832C2.1
基因别名: 2400004H09Rik; Atad3; ATAD3A; Kiaa1273; mKIAA1273; Tob3
UniProt ID: (Human) Q9NVI7, (Mouse) Q925I1
Entrez Gene ID: (Human) 55210, (Mouse) 108888