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产品信息
PA5-20996
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 19 amino acid peptide near the amino terminus of human ATP11B.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152699
产品详细信息
A suggested positive control is K562 cell lysate.
PA5-20996 can be used with blocking peptide PEP-1110.
靶标信息
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATPase class VI type 11B; ATPase IR; ATPase, class VI, type 11B; P4-ATPase flippase complex alpha subunit ATP11B; Phospholipid-transporting ATPase IF; probable phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
基因别名: 1110019I14Rik; ATP11B; ATPIF; ATPIR; KIAA0956; mKIAA0956
UniProt ID: (Human) Q9Y2G3, (Mouse) Q6DFW5
Entrez Gene ID: (Human) 23200, (Mouse) 76295
