Proteintech

ATP6 Polyclonal Antibody

ATP6 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 8

ATP6 Antibody (55313-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HepG2 cells using 55313-1-AP (ATP6 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ATP6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

产品信息

55313-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看38篇已发表文章 38篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

查看1篇已发表文章 1篇已发表文章

产品规格

已发表种属

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.27 mg/mL

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

靶标信息

The MT-ATP6 gene provides information for making a protein that is essential for normal mitochondrial function. Mitochondria are structures within cells that convert the energy from food into a form that cells can use. These cellular structures produce energy through a process called oxidative phosphorylation, which uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell's main energy source. The MT-ATP6 protein forms one part (subunit) of a large enzyme called ATP synthase. This enzyme, which is also known as complex V, is responsible for the final step of oxidative phosphorylation. Specifically, one segment of ATP synthase allows positively charged particles, called protons, to flow across a specialized membrane inside mitochondria. Another segment of the enzyme uses the energy created by this proton flow to convert a molecule called adenosine diphosphate (ADP) to ATP.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria.

Life science alliance

Kim JY,Atanassov I,Dethloff F,Kroczek L,Langer T

Fri Sep 01 00:00:00 EDT 2023

Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m³C modification.

Cell stem cell

Zhang F,Yoon K,Zhang DY,Kim NS,Ming GL,Song H

Thu Mar 02 00:00:00 EST 2023

PBDE-47 induces impairment of mitochondrial biogenesis and subsequent neurotoxicity through miR-128-3p/PGC-1α axis.

Toxicological sciences : an official journal of the Society of Toxicology

Tian Z,Li J,Song L,Xie L,Li D,Xia T,Wang A

Tue Jan 31 00:00:00 EST 2023

Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.

The Science of the total environment

Li D,Zhao Q,Xie L,Wang C,Tian Z,Tang H,Xia T,Wang A

Sat Apr 15 00:00:00 EDT 2023

Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway.

Cell

Zhang J,Simpson CM,Berner J,Chong HB,Fang J,Ordulu Z,Weiss-Sadan T,Possemato AP,Harry S,Takahashi M,Yang TY,Richter M,Patel H,Smith AE,Carlin AD,Hubertus de Groot AF,Wolf K,Shi L,Wei TY,Dürr BR,Chen NJ,Vornbäumen T,Wichmann NO,Mahamdeh MS,Pooladanda V,Matoba Y,Kumar S,Kim E,Bouberhan S,Oliva E,Rueda BR,Soberman RJ,Bardeesy N,Liau BB,Lawrence M,Stokes MP,Beausoleil SA,Bar-Peled L

Thu May 25 00:00:00 EDT 2023

Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway.

bioRxiv : the preprint server for biology

Zhang J,Simpson CM,Berner J,Chong HB,Fang J,Sahin ZO,Weiss-Sadan T,Possemato AP,Harry S,Takahashi M,Yang TY,Richter M,Patel H,Smith AE,Carlin AD,Hubertus de Groot AF,Wolf K,Shi L,Wei TY,Dürr BR,Chen NJ,Vornbäumen T,Wichmann NO,Pooladanda V,Matoba Y,Kumar S,Kim E,Bouberhan S,Olivia E,Rueda B,Bardeesy N,Liau B,Lawrence M,Stokes MP,Beausoleil SA,Bar-Peled L

Sat Mar 11 00:00:00 EST 2023

TMPRSS12 Functions in Meiosis and Spermiogenesis and Is Required for Male Fertility in Mice.

Frontiers in cell and developmental biology

Zhang J,Zhou X,Wan D,Yu L,Chen X,Yan T,Wu Z,Zheng M,Zhu F,Zhu H

Sat Jul 16 00:00:00 EDT 2022

LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.

Development (Cambridge, England)

Zhao K,Huang X,Zhao W,Lu B,Yang Z

Tue Mar 15 00:00:00 EDT 2022

Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H⁺] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes.

Toxicology and applied pharmacology

Zhang Y,Liang X,Guan J,Jin J,Zhang Y,Xu F,Fu J

Tue Mar 15 00:00:00 EDT 2022

MOTS-c increases in skeletal muscle following long-term physical activity and improves acute exercise performance after a single dose.

Physiological reports

Hyatt JK

Fri Jul 01 00:00:00 EDT 2022

Nonstop mRNAs generate a ground state of mitochondrial gene expression noise.

Science advances

Ng KY,Lutfullahoglu Bal G,Richter U,Safronov O,Paulin L,Dunn CD,Paavilainen VO,Richer J,Newman WG,Taylor RW,Battersby BJ

Wed Nov 16 00:00:00 EST 2022

Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.

The Journal of cell biology

Oshima Y,Cartier E,Boyman L,Verhoeven N,Polster BM,Huang W,Kane M,Lederer WJ,Karbowski M

Mon Jun 07 00:00:00 EDT 2021

Mtu1 defects are correlated with reduced osteogenic differentiation.

Cell death & disease

He Q,Zhao Q,Li Q,Pan R,Li X,Chen Y

Mon Jan 11 00:00:00 EST 2021

TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.

Nature structural & molecular biology

Zuo X,Zhou J,Li Y,Wu K,Chen Z,Luo Z,Zhang X,Liang Y,Esteban MA,Zhou Y,Fu XD

Mon Feb 01 00:00:00 EST 2021

Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.

Free radical biology & medicine

Gu X,Liu Y,Wang N,Zhen J,Zhang B,Hou S,Cui Z,Wan Q,Feng H

Sat Feb 20 00:00:00 EST 2021

A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.

Cellular and molecular gastroenterology and hepatology

Sun D,Niu Z,Zheng HX,Wu F,Jiang L,Han TQ,Wei Y,Wang J,Jin L

Mon Mar 07 00:00:00 EST 2022

Modulation of OSCP mitigates mitochondrial and synaptic deficits in a mouse model of Alzheimer's pathology.

Neurobiology of aging

Gauba E,Sui S,Tian J,Driskill C,Jia K,Yu C,Rughwani T,Wang Q,Kroener S,Guo L,Du H

Mon Feb 01 00:00:00 EST 2021

Tissue-specific expression atlas of murine mitochondrial tRNAs.

The Journal of biological chemistry

He Q,He X,Xiao Y,Zhao Q,Ye Z,Cui L,Chen Y,Guan MX

Sun Aug 01 00:00:00 EDT 2021

ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells.

Frontiers in cell and developmental biology

Yang Y,Li C,Gu X,Zhen J,Zhu S,Lv T,Wan Q,Liu Y

Fri Aug 27 00:00:00 EDT 2021

TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.

Frontiers in cell and developmental biology

Liang X,He M,Zhu B,Zhu Y,He X,Liu D,Wei Q

Wed Sep 08 00:00:00 EDT 2021

SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.

iScience

Ma Y,Zhu S,Lv T,Gu X,Feng H,Zhen J,Xin W,Wan Q

Fri Aug 21 00:00:00 EDT 2020

SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride.

Theranostics

Zhao Q,Tian Z,Zhou G,Niu Q,Chen J,Li P,Dong L,Xia T,Zhang S,Wang A

Thu May 13 00:00:00 EDT 2021

SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride.

Theranostics

Zhao Q,Tian Z,Zhou G,Niu Q,Chen J,Li P,Dong L,Xia T,Zhang S,Wang A

Thu May 13 00:00:00 EDT 2021

SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride.

Theranostics

Zhao Q,Tian Z,Zhou G,Niu Q,Chen J,Li P,Dong L,Xia T,Zhang S,Wang A

Thu May 13 00:00:00 EDT 2021

SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride.

Theranostics

Zhao Q,Tian Z,Zhou G,Niu Q,Chen J,Li P,Dong L,Xia T,Zhang S,Wang A

Thu May 13 00:00:00 EDT 2021

Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis.

Diabetes

Tian N,Liu Q,Li Y,Tong L,Lu Y,Zhu Y,Zhang P,Chen H,Hu L,Meng J,Feng M,Li M,Zheng L,Li B,Xu T,Wu L,Tong X

Wed Jul 01 00:00:00 EDT 2020

Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNA^Thr Gene.

Journal of diabetes research

Li K,Wu L,Liu J,Lin W,Qi Q,Zhao T

Mon Dec 14 00:00:00 EST 2020

A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.

Nucleic acids research

Jia Z,Zhang Y,Li Q,Ye Z,Liu Y,Fu C,Cang X,Wang M,Guan MX

Thu Feb 28 00:00:00 EST 2019

A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.

Nucleic acids research

Jia Z,Zhang Y,Li Q,Ye Z,Liu Y,Fu C,Cang X,Wang M,Guan MX

Thu Feb 28 00:00:00 EST 2019

Mitochondrial stress response triggered by defects in protein synthesis quality control.

Life science alliance

Richter U,Ng KY,Suomi F,Marttinen P,Turunen T,Jackson C,Suomalainen A,Vihinen H,Jokitalo E,Nyman TA,Isokallio MA,Stewart JB,Mancini C,Brusco A,Seneca S,Lombès A,Taylor RW,Battersby BJ

Fri Feb 01 00:00:00 EST 2019

Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3.

Cell death & disease

Fu R,Yang P,Li Z,Liu W,Amin S,Li Z

Wed Aug 07 00:00:00 EDT 2019

The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα.

Nature communications

Iershov A,Nemazanyy I,Alkhoury C,Girard M,Barth E,Cagnard N,Montagner A,Chretien D,Rugarli EI,Guillou H,Pende M,Panasyuk G

Fri Apr 05 00:00:00 EDT 2019

EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.

Molecular genetics & genomic medicine

Sha Y,Liu W,Huang X,Li Y,Ji Z,Mei L,Lin S,Kong S,Lu J,Kong L,Zhu X,Lu Z,Ding L

Thu Aug 01 00:00:00 EDT 2019

EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.

Molecular genetics & genomic medicine

Sha Y,Liu W,Huang X,Li Y,Ji Z,Mei L,Lin S,Kong S,Lu J,Kong L,Zhu X,Lu Z,Ding L

Thu Aug 01 00:00:00 EDT 2019

Protective effects of β- nicotinamide adenine dinucleotide against motor deficits and dopaminergic neuronal damage in a mouse model of Parkinson's disease.

Progress in neuro-psychopharmacology & biological psychiatry

Shan C,Gong YL,Zhuang QQ,Hou YF,Wang SM,Zhu Q,Huang GR,Tao B,Sun LH,Zhao HY,Li ST,Liu JM

Fri Aug 30 00:00:00 EDT 2019

Leber's hereditary optic neuropathy caused by a mutation in mitochondrial tRNA^Thr in eight Chinese pedigrees.

Mitochondrion

Zhang J,Ji Y,Liu X,Chen J,Wang B,Zhang M,Guan MX

Sat Sep 01 00:00:00 EDT 2018

Leber's hereditary optic neuropathy caused by a mutation in mitochondrial tRNA^Thr in eight Chinese pedigrees.

Mitochondrion

Zhang J,Ji Y,Liu X,Chen J,Wang B,Zhang M,Guan MX

Sat Sep 01 00:00:00 EDT 2018

Biallelic mutations in mitochondrial tryptophanyl-tRNA synthetase cause Levodopa-responsive infantile-onset Parkinsonism.

Clinical genetics

Burke EA,Frucht SJ,Thompson K,Wolfe LA,Yokoyama T,Bertoni M,Huang Y,Sincan M,Adams DR,Taylor RW,Gahl WA,Toro C,Malicdan MCV

Thu Mar 01 00:00:00 EST 2018

Biallelic mutations in mitochondrial tryptophanyl-tRNA synthetase cause Levodopa-responsive infantile-onset Parkinsonism.

Clinical genetics

Burke EA,Frucht SJ,Thompson K,Wolfe LA,Yokoyama T,Bertoni M,Huang Y,Sincan M,Adams DR,Taylor RW,Gahl WA,Toro C,Malicdan MCV

Thu Mar 01 00:00:00 EST 2018

RNA modification landscape of the human mitochondrial tRNA^Lys regulates protein synthesis.

Nature communications

Richter U,Evans ME,Clark WC,Marttinen P,Shoubridge EA,Suomalainen A,Wredenberg A,Wedell A,Pan T,Battersby BJ

Thu Sep 27 00:00:00 EDT 2018

RNA modification landscape of the human mitochondrial tRNA^Lys regulates protein synthesis.

Nature communications

Richter U,Evans ME,Clark WC,Marttinen P,Shoubridge EA,Suomalainen A,Wredenberg A,Wedell A,Pan T,Battersby BJ

Thu Sep 27 00:00:00 EDT 2018

A hypertension-associated mitochondrial DNA mutation introduces an m¹G37 modification into tRNA^Met, altering its structure and function.

The Journal of biological chemistry

Zhou M,Xue L,Chen Y,Li H,He Q,Wang B,Meng F,Wang M,Guan MX

Fri Jan 26 00:00:00 EST 2018

A hypertension-associated mitochondrial DNA mutation introduces an m¹G37 modification into tRNA^Met, altering its structure and function.

The Journal of biological chemistry

Zhou M,Xue L,Chen Y,Li H,He Q,Wang B,Meng F,Wang M,Guan MX

Fri Jan 26 00:00:00 EST 2018

Base-Resolution Mapping Reveals Distinct m¹A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts.

Molecular cell

Li X,Xiong X,Zhang M,Wang K,Chen Y,Zhou J,Mao Y,Lv J,Yi D,Chen XW,Wang C,Qian SB,Yi C

Thu Dec 07 00:00:00 EST 2017

Base-Resolution Mapping Reveals Distinct m¹A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts.

Molecular cell

Li X,Xiong X,Zhang M,Wang K,Chen Y,Zhou J,Mao Y,Lv J,Yi D,Chen XW,Wang C,Qian SB,Yi C

Thu Dec 07 00:00:00 EST 2017

Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.

Scientific reports

Hu D,Cao S,Zhang G,Xiao Y,Liu S,Shang Y

Thu Oct 19 00:00:00 EDT 2017

Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.

Scientific reports

Hu D,Cao S,Zhang G,Xiao Y,Liu S,Shang Y

Thu Oct 19 00:00:00 EDT 2017

Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.

Scientific reports

Hu D,Cao S,Zhang G,Xiao Y,Liu S,Shang Y

Thu Oct 19 00:00:00 EDT 2017

A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNA^Leu(UUR).

The Journal of biological chemistry

Zhou M,Wang M,Xue L,Lin Z,He Q,Shi W,Chen Y,Jin X,Li H,Jiang P,Guan MX

Fri Aug 25 00:00:00 EDT 2017

A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNA^Leu(UUR).

The Journal of biological chemistry

Zhou M,Wang M,Xue L,Lin Z,He Q,Shi W,Chen Y,Jin X,Li H,Jiang P,Guan MX

Fri Aug 25 00:00:00 EDT 2017

Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.

Nature communications

Beck SJ,Guo L,Phensy A,Tian J,Wang L,Tandon N,Gauba E,Lu L,Pascual JM,Kroener S,Du H

Fri May 06 00:00:00 EDT 2016

Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.

Nature communications

Beck SJ,Guo L,Phensy A,Tian J,Wang L,Tandon N,Gauba E,Lu L,Pascual JM,Kroener S,Du H

Fri May 06 00:00:00 EDT 2016

Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.

Nature communications

Beck SJ,Guo L,Phensy A,Tian J,Wang L,Tandon N,Gauba E,Lu L,Pascual JM,Kroener S,Du H

Fri May 06 00:00:00 EDT 2016

ATP6 Polyclonal Antibody

ATP6 Antibody (55313-1-AP) in ICC/IF

产品信息

55313-1-AP

免疫印迹 (WB)

免疫组化 (IHC)

免疫细胞化学 (ICC/IF)

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

保存条件

运输条件

靶标信息

性能保障

随时为您服务

Your items have has been added!