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Acetylcholinesterase Antibody (PA5-18348) in ICC/IF
Immunocytochemistry analysis of Acetylcholinesterase using Acetylcholinesterase Polyclonal Antibody (Product # PA5-18348) in paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing nuclear, membrane and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG ... View More
产品信息
PA5-18348
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (QFDHYSKQDRCSDL) corresponding to the C-terminus amino acids of ACHE
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_11000727
产品详细信息
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acetylcholinesterase; acetylcholinesterase (Yt blood group); AChE; apoptosis-related acetylcholinesterase; EC 3.1.1.7; OTTHUMP00000211349; OTTHUMP00000211356; Yt blood group
基因别名: ACEE; ACHE; ARACHE; N-ACHE; YT
UniProt ID: (Human) Q2M324
Entrez Gene ID: (Human) 43
acetylcholine catabolic process in synaptic cleft
regulation of receptor recycling
osteoblast development
DNA replication
acetylcholine catabolic process
phosphatidylcholine biosynthetic process
cell adhesion
nervous system development
synapse assembly
muscle organ development
cell proliferation
response to wounding
receptor internalization
negative regulation of synaptic transmission, cholinergic
neurotransmitter biosynthetic process
amyloid precursor protein metabolic process
neurotransmitter receptor biosynthetic process
positive regulation of protein secretion
protein tetramerization
retina development in camera-type eye
