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In Western blot applications, this antibody detects a band at ~220kDa. A suggested positive control is K562 cell lysate.
PA5-19948 can be used with blocking peptide PEP-0073.
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Acinus; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107; functional spliceosome-associated protein 152
基因别名: ACIN1; ACINUS; ACN; fSAP152; KIAA0670
UniProt ID: (Human) Q9UKV3
Entrez Gene ID: (Human) 22985