Invitrogen

Adenosine Deaminase Polyclonal Antibody

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抗体检测数据 (4)

Adenosine Deaminase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Adenosine Deaminase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Adenosine Deaminase Antibody (PA5-80316) in IHC (P)

Immunohistochemical staining of human Adenosine Deaminase in human duodenum with Adenosine Deaminase Polyclonal Antibody (Product # PA5-80316, 1:2,000 dilution, formalin-fixed paraffin embedded sections).

Adenosine Deaminase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Adenosine Deaminase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Adenosine Deaminase Antibody in Western Blot (WB)

Adenosine Deaminase Antibody in Immunoprecipitation (IP)

Product Image Gallery

Adenosine Deaminase Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical staining of human Adenosine Deaminase in human duodenum with Adenosine Deaminase Polyclonal Antibody (Product # PA5-80316, 1:2,000 dilution, formalin-fixed paraffin embedded sections).

Adenosine Deaminase Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical staining of human Adenosine Deaminase in human brain with Adenosine Deaminase Polyclonal Antibody (Product # PA5-80316, 1:2,000 dilution, formalin-fixed paraffin embedded sections).

Adenosine Deaminase Antibody in Western Blot (WB) — Western Blot using Adenosine Deaminase Polyclonal Antibody (Product # PA5-80316) at 1:500 dilution. Lane A: Jurkat Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1:10,000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 41 kDa.

Adenosine Deaminase Antibody in Immunoprecipitation (IP) — Adenosine Deaminase Immunoprecipitation using: Lane A: 0.5 mg mouse brain tissue lysate 4 µL with Adenosine Deaminase Polyclonal Antibody (Product # PA5-80316) and 60 μg of Immunomagnetic beads Protein A/G.Primary antibody: Adenosine Deaminase Polyclonal Antibody, at 1:100 dilution. Secondary antibody: Goat Anti-Rabbit IgG (H+L) /HRP at 1:10,000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 26 kDa. Observed band size: 28 kDa.

产品信息

PA5-80316

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

免疫组化（石蜡） (IHC (P))

1:500-1:3,000

-

免疫沉淀 (IP)

1-5 µL/mg of lysate

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to the C-terminus of the Human Adenosine Deaminase/ADA

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7

内含物

0.03% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2787645

产品详细信息

This antibody has specificity for Human Adenosine Deaminase/ADA.

靶标信息

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Adenosine aminohydrolase; Adenosine deaminase; RP11-61L14.5

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基因别名: ADA; ADA1

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UniProt ID: (Human) P00813

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Entrez Gene ID: (Human) 100

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purine nucleoside binding adenosine deaminase activity protein binding zinc ion binding deaminase

参与通路

response to hypoxia histamine secretion trophectodermal cell differentiation liver development placenta development germinal center B cell differentiation positive regulation of germinal center formation negative regulation of leukocyte migration negative regulation of mature B cell apoptotic process adenosine catabolic process deoxyadenosine catabolic process aging purine ribonucleoside monophosphate biosynthetic process positive regulation of heart rate positive regulation of B cell proliferation purine nucleotide salvage positive regulation of T cell differentiation in thymus response to vitamin E regulation of cell-cell adhesion mediated by integrin T cell activation negative regulation of circadian sleep/wake cycle, non-REM sleep response to drug response to hydrogen peroxide purine-containing compound salvage hypoxanthine salvage response to morphine positive regulation of smooth muscle contraction dATP catabolic process inosine biosynthetic process xanthine biosynthetic process positive regulation of alpha-beta T cell differentiation lung alveolus development Peyer's patch development embryonic digestive tract development negative regulation of inflammatory response positive regulation of calcium-mediated signaling positive regulation of T cell receptor signaling pathway negative regulation of adenosine receptor signaling pathway negative regulation of penile erection negative regulation of thymocyte apoptotic process negative regulation of mucus secretion