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产品信息
MA1-82977
应用
建议稀释比
已发表文章
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG2a/IgM
分类
Monoclonal
类型
Antibody
克隆号
7C11
抗原
Hexon antigen of human and canine adenoviruses (Type 1).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
<0.1% sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_926847
产品详细信息
It is likely that this antibody will react with all mammalian Adenoviruses.
Mouse anti Adenovirus Hexon antibody, clone 7C11 reacts with human, canine, bovine, monkey and rat adenoviruses. It is very likely that it will react with all mammalian Adenoviruses.
靶标信息
Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). 49 human adenovirus serotypes have been discovered and divided into six subgroups, A to E, based on observation. They are an important cause of respiratory illness, conjunctivitis, gastroenteritis, and have more recently been recognized as a potential cause of sexually transmitted diseases. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterized by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated, causing disease. Adenovirus vectors, particularly those based on Ad5, have shown great promise for the development of gene therapy protocols and have been used for clinical purpose. Adenoviruses capsids have three principal protein components: the hexon, the penton, and the fiber. Hexon protein is a major coat protein (240 hexons per particle). Each hexon capsomere is homotrimer of the hexon protein, a complex protein of over 900 residues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adeno Virus; Adeno Virus 1; AdV; AdV-1; HADV; HADV-1
