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产品信息
67909-1-IG
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1C8H3
抗原
AARS Fusion Protein Ag11151
偶联物
形式
Liquid
浓度
1000 µg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Aliquoting is unnecessary for -20°C storage.
靶标信息
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E. coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AARS; alanine tRNA ligase 1, cytoplasmic; Alanine--tRNA ligase, cytoplasmic; alanine--tRNA ligase, cytoplasmic {ECO:0000255|HAMAP-Rule:MF_03133}; Alanyl-tRNA synthetase; alanyl-tRNA synthetase {ECO:0000255|HAMAP-Rule:MF_03133}; alanyl-tRNA synthetase, cytoplasmic; AlaRS; alaRS {ECO:0000255|HAMAP-Rule:MF_03133}; Protein lactyltransferase AARS1; Protein sticky; Renal carcinoma antigen NY-REN-42; Sti
基因别名: AARS; AARS1; AI316495; C76919; CMT2N; EIEE29; sti
UniProt ID: (Human) P49588, (Mouse) Q8BGQ7, (Rat) P50475
Entrez Gene ID: (Human) 16, (Mouse) 234734, (Rat) 292023
tRNA binding
aminoacyl-tRNA editing activity
alanine-tRNA ligase activity
ATP binding
zinc ion binding
amino acid binding
nucleotide binding
nucleic acid binding
RNA binding
aminoacyl-tRNA ligase activity
protein binding
ligase activity
ligase activity, forming aminoacyl-tRNA and related compounds
metal ion binding
aminoacyl-tRNA synthetase
hair follicle development
tRNA modification
tRNA aminoacylation for protein translation
alanyl-tRNA aminoacylation
regulation of translational fidelity
protein folding
tRNA processing
cerebellar Purkinje cell layer development
endoplasmic reticulum unfolded protein response
response to amino acid
negative regulation of neuron apoptotic process
neuromuscular process controlling balance
translation
cellular response to unfolded protein
tRNA aminoacylation
skin development
neuromuscular process
