Invitrogen

Amphiphysin Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他7个Amphiphysin抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

高级验证 (1)

图: 1 / 1

Amphiphysin Antibody (PA5-82702)

Relative expression in different tissues in IHC: Detection of differential expression levels of Amphiphysin demonstrates antibody specificity. Immunohistochemical analysis of Amphiphysin using anti-Amphiphysin Polyclonal Antibody (Product #PA5-82702), shows significant staining of Amphiphysin in cerebral cortex and shows minimal or weak staining in tonsil tissues. The relative expression levels of Amphiphy... View More

Product Image Gallery

产品信息

PA5-82702

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化 (IHC)

1:1,000-1:2,500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human AMPH. Recombinant protein control fragment (Product #RP-92625).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.4 mg/mL

纯化类型

Anitgen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2789858

产品详细信息

Immunogen sequence: PGFLYKVETL HDFEAANSDE LTLQRGDVVL VVPSDSEADQ DAGWLVGVKE SDWLQYRDLA TYKGLFPENF TRRL

靶标信息

Amphiphysins, members of the BAR (Bin-Amphiphysin-Rvsp) protein super family, play a key role in clathrin-mediated endocytosis of synaptic vesicles (SVs). All members of the BAR family share a highly conserved N-terminal BAR domain and a C-terminal Src homology (SH3) domain. Two isoforms of amphiphysin have been identified and act in concert as a heterodimer. Amphiphysins interact via its carboxy-terminal SH3 domain with dynamin, synaptojanin and clathrin. These complexes are implicated in synaptic vesicle recycling at nerve terminal. Amphiphysins were also identified as the dominant autoantigen in paraneoplastic Stiff-Man Syndrome.

仅用于科研。不用于诊断过程。未经明确授权不得转售。