Invitrogen

Angiopoietin 1 Monoclonal Antibody (E1)

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抗体检测数据 (3)

Angiopoietin 1 Antibody in Western Blot (WB)

Angiopoietin 1 Antibody in Western Blot (WB)

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Angiopoietin 1 Antibody (MA5-41549) in WB

Western blot analysis of Angiopoietin 1 in Lane 1: Mouse Heart lysate; Lane 2: Mouse Liver lysate. Samples were incubated with monoclonal antibody (Product # MA5-41549) at a dilution of 3 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 0.2 µg/mL.

Angiopoietin 1 Antibody in Western Blot (WB)

Angiopoietin 1 Antibody in Western Blot (WB)

Angiopoietin 1 Antibody in Western Blot (WB)

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Angiopoietin 1 Antibody in Western Blot (WB) — Western blot analysis of Angiopoietin 1 in Lane 1: Mouse Heart lysate; Lane 2: Mouse Liver lysate. Samples were incubated with monoclonal antibody (Product # MA5-41549) at a dilution of 3 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 0.2 µg/mL.

Angiopoietin 1 Antibody in Western Blot (WB) — Western blot analysis of Angiopoietin 1 in mouse liver lysate. Samples were incubated in Angiopoietin 1 Monoclonal antibody (Product # MA5-41549) at a dilution of 3 µg/mL followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 0.2 µg/mL.

Angiopoietin 1 Antibody in Western Blot (WB) — Western blot analysis of Angiopoietin 1 in recombinant human ANGPT1. Sample was incubated with monoclonal antibody (Product # MA5-41549).

产品信息

MA5-41549

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.01-2 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

E1

抗原

Recombinant protein Angiopoietin 1. The antigen corresponds to amino acid range 284-452 of the target protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20°C

运输条件

Wet ice

RRID

AB_2899032

靶标信息

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ANG-1; Angiopoietin-1

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基因别名: AGP1; AGPT; ANG1; ANGPT1; KIAA0003

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UniProt ID: (Human) Q15389

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Entrez Gene ID: (Human) 284

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Ras guanyl-nucleotide exchange factor activity receptor tyrosine kinase binding intercellular signal molecule

参与通路

MAPK cascade in utero embryonic development negative regulation of protein phosphorylation regulation of endothelial cell proliferation sprouting angiogenesis positive regulation of receptor internalization negative regulation of cytokine secretion involved in immune response negative regulation of cell adhesion activation of transmembrane receptor protein tyrosine kinase activity positive regulation of endothelial cell migration positive regulation of phosphatidylinositol 3-kinase signaling regulation of skeletal muscle satellite cell proliferation hemopoiesis cell differentiation heparin biosynthetic process positive regulation of protein ubiquitination cell-substrate adhesion regulation of tumor necrosis factor production positive regulation of peptidyl-serine phosphorylation protein localization to cell surface negative regulation of protein import into nucleus negative regulation of apoptotic process negative regulation of vascular permeability regulation of I-kappaB kinase/NF-kappaB signaling regulation of protein binding negative regulation of neuron apoptotic process positive regulation of blood vessel endothelial cell migration positive regulation of GTPase activity positive regulation of cell adhesion Tie signaling pathway positive regulation of peptidyl-tyrosine phosphorylation leukocyte migration positive chemotaxis positive regulation of protein kinase B signaling positive regulation of ERK1 and ERK2 cascade glomerulus vasculature development negative regulation of endothelial cell apoptotic process regulation of macrophage migration inhibitory factor signaling pathway