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Invitrogen
Apelin Receptor Recombinant Rabbit Monoclonal Antibody (5H5L9)
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Apelin Receptor Antibody (702069) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized HeLa cells for detection of endogenous APLNR using Anti-APLNR Recombinant Rabbit Monoclonal Antibody (Product # 702069, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localizat... View More
产品信息
702069
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5H5L9
抗原
Peptides corresponding to Human APLNR (aa 6-20, 52-66)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2633058
产品详细信息
This antibody is predicted to react with Monkey, Rabbit, Horse and Dog
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
APLNR (Apelin Receptor) is a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: angiotensin II receptor-like 1; Angiotensin receptor-like 1; Apelin receptor; APJ (apelin) receptor; APJ receptor; G protein-coupled receptor APJ; G-protein coupled receptor APJ; G-protein coupled receptor HG11; HG11 orphan receptor; MSR
基因别名: AGTRL1; APJ; APJR; APLNR; HG11; msr/apj
UniProt ID: (Human) P35414, (Mouse) Q9WV08
Entrez Gene ID: (Human) 187, (Mouse) 23796
