Product References
Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic functions.
Bioactive materials
Mandakhbayar N,Ji Y,El-Fiqi A,Patel KD,Yoon DS,Dashnyam K,Bayaraa O,Jin G,Tsogtbaatar K,Kim TH,Lee JH,Kim HW
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Western Blot
Mon Jan 01 00:00:00 EST 2024
Magnesium implant degradation provides immunomodulatory and proangiogenic effects and attenuates peri-implant fibrosis in soft tissues.
Bioactive materials
Ben Amara H,Martinez DC,Shah FA,Loo AJ,Emanuelsson L,Norlindh B,Willumeit-Römer R,Plocinski T,Swieszkowski W,Palmquist A,Omar O,Thomsen P
PA5-29645 was used in Immunohistochemistry to determine the temporo-spatial cell distribution and behavior in relation to sequential changes of pure Mg implant surface properties and Mg2+ release.
Tue Aug 01 00:00:00 EDT 2023
Magnesium implant degradation provides immunomodulatory and proangiogenic effects and attenuates peri-implant fibrosis in soft tissues.
Bioactive materials
Ben Amara H,Martinez DC,Shah FA,Loo AJ,Emanuelsson L,Norlindh B,Willumeit-Römer R,Plocinski T,Swieszkowski W,Palmquist A,Omar O,Thomsen P
PA5-29645 was used in Immunohistochemistry to determine the temporo-spatial cell distribution and behavior in relation to sequential changes of pure Mg implant surface properties and Mg2+ release.
Tue Aug 01 00:00:00 EDT 2023
Oxalate disrupts monocyte and macrophage cellular function via Interleukin-10 and mitochondrial reactive oxygen species (ROS) signaling.
Redox biology
Kumar P,Laurence E,Crossman DK,Assimos DG,Murphy MP,Mitchell T
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Western Blot
Wed Nov 01 00:00:00 EDT 2023
Target-Specific Nanoparticle Polyplex Down-Regulates Mutant Kras to Prevent Pancreatic Carcinogenesis and Halt Tumor Progression.
International journal of molecular sciences
Smith JP,Chen W,Shivapurkar N,Gerber M,Tucker RD,Kallakury B,Dasa SSK,Kularatne RN,Stern ST
PA5-29645 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to propose that precision therapy with target-specific NPs provides a novel approach to slow progression of advanced pancreatic cancer and also prevents the development of pancreatic cancer in high-risk subjects without toxicity to other tissues.
Sun Jan 01 00:00:00 EST 2023
Dual stimulus responsive borosilicate glass (BSG) scaffolds promote diabetic alveolar bone defectsrepair by modulating macrophage phenotype.
Bioactive materials
Tian P,Zhao L,Kim J,Li X,Liu C,Cui X,Liang T,Du Y,Chen X,Pan H
PA5-29645 was used in Western Blotting to develop glucose and hydrogen peroxide dual-responsive borosilicate glass (BSG) scaffolds loaded with epigallocatechin gallate (EGCG) to synergistically modulate the abnormal inflammation of diabetic alveolar bone defects.
Tue Aug 01 00:00:00 EDT 2023
Effects of a neurokinin-1 receptor antagonist in the acute phase after thoracic spinal cord injury in a rat model.
Frontiers in molecular neuroscience
Zheng G,Harms AK,Tail M,Zhang H,Nimmo A,Skutella T,Kiening K,Unterberg A,Zweckberger K,Younsi A
PA5-29645 was used in Immunohistochemistry to observe the effect of antagonizing the binding of the neuropeptide Substance-P (SP) to its neurokinin-1 (NK1) receptor in a rodent spinal cord injury (SCI) model.
Wed May 31 00:00:00 EDT 2023
The polarization of microglia and infiltrated macrophages in the injured mice spinal cords: a dynamic analysis.
PeerJ
Li JL,Fu GQ,Wang YY,Bian MM,Xu YM,Zhang L,Chen YQ,Zhang N,Ding SQ,Wang R,Fang R,Tang J,Hu JG,Lü HZ
PA5-29645 was used in Immunohistochemistry-immunofluorescence to study if M1 cells in injured spinal cords were mainly derived from MG rather than infiltrating Mø.
Tue Feb 28 00:00:00 EST 2023
Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization.
CNS neuroscience & therapeutics
Xue MT,Sheng WJ,Song X,Shi YJ,Geng ZJ,Shen L,Wang R,Lü HZ,Hu JG
PA5-29645 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal a novel effect of ATL-III in the regulation of microglial/macrophage polarization and provides initial evidence that ATL-III has potential therapeutic benefits in SCI rats.
Fri Jul 01 00:00:00 EDT 2022
Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization.
CNS neuroscience & therapeutics
Xue MT,Sheng WJ,Song X,Shi YJ,Geng ZJ,Shen L,Wang R,Lü HZ,Hu JG
PA5-29645 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal a novel effect of ATL-III in the regulation of microglial/macrophage polarization and provides initial evidence that ATL-III has potential therapeutic benefits in SCI rats.
Fri Jul 01 00:00:00 EDT 2022
Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization.
CNS neuroscience & therapeutics
Xue MT,Sheng WJ,Song X,Shi YJ,Geng ZJ,Shen L,Wang R,Lü HZ,Hu JG
PA5-29645 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal a novel effect of ATL-III in the regulation of microglial/macrophage polarization and provides initial evidence that ATL-III has potential therapeutic benefits in SCI rats.
Fri Jul 01 00:00:00 EDT 2022
Histone methyltransferase enhancer of zeste 2 polycomb repressive complex 2 subunit exacerbates inflammation in depression rats by modulating microglia polarization.
Bioengineered
Huang X,Yang Q,Xie L,Lei S
PA5-29645 was used in Western Blot to investigate the mechanism of EZH2 on depression.
Tue Mar 01 00:00:00 EST 2022
Histone methyltransferase enhancer of zeste 2 polycomb repressive complex 2 subunit exacerbates inflammation in depression rats by modulating microglia polarization.
Bioengineered
Huang X,Yang Q,Xie L,Lei S
PA5-29645 was used in Western Blot to investigate the mechanism of EZH2 on depression.
Tue Mar 01 00:00:00 EST 2022
Epithelial arginase-1 is a key mediator of age-associated delayed healing in vaginal injury.
Frontiers in endocrinology
Wilkinson HN,Reubinoff B,Shveiky D,Hardman MJ,Menachem-Zidon OB
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunocytochemistry
Tue Aug 30 00:00:00 EDT 2022
Anti-Inflammatory CDGSH Iron-Sulfur Domain 2: A Biomarker of Central Nervous System Insult in Cellular, Animal Models and Patients.
Biomedicines
Kung WM,Lin CC,Chen WJ,Jiang LL,Sun YY,Hsieh KH,Lin MS
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Western Blot
Sun Mar 27 00:00:00 EDT 2022
Intermittent lipid nanoparticle mRNA administration prevents cortical dysmyelination associated with arginase deficiency.
Molecular therapy. Nucleic acids
Khoja S,Liu XB,Truong B,Nitzahn M,Lambert J,Eliav A,Nasser E,Randolph E,Burke KE,White R,Zhu X,Martini PGV,Nissim I,Cederbaum SD,Lipshutz GS
PA5-29645 was used in Immunohistochemistry and Western Blotting to describe leukodystrophy as a significant component of the central nervous system features of arginase deficiency.
Tue Jun 14 00:00:00 EDT 2022
Intermittent lipid nanoparticle mRNA administration prevents cortical dysmyelination associated with arginase deficiency.
Molecular therapy. Nucleic acids
Khoja S,Liu XB,Truong B,Nitzahn M,Lambert J,Eliav A,Nasser E,Randolph E,Burke KE,White R,Zhu X,Martini PGV,Nissim I,Cederbaum SD,Lipshutz GS
PA5-29645 was used in Immunohistochemistry and Western Blotting to describe leukodystrophy as a significant component of the central nervous system features of arginase deficiency.
Tue Jun 14 00:00:00 EDT 2022
Immunomodulation of Acellular Dermal Matrix Through Interleukin 4 Enhances Vascular Infiltration.
Annals of plastic surgery
Cottler PS,Kang H,Nash V,Salopek L,Bruce AC,Spiller KL,Campbell CA
PA5-29645 was used in Immunohistochemistry to investigate the potential of interleukin-4 (IL-4) adsorbed onto acellular dermal matrix (ADM) as a means to improve vascularization and integration in implant-based breast reconstruction.
Wed Jun 01 00:00:00 EDT 2022
Attenuation of clinical and immunological outcomes during SARS-CoV-2 infection by ivermectin.
EMBO molecular medicine
de Melo GD,Lazarini F,Larrous F,Feige L,Kornobis E,Levallois S,Marchio A,Kergoat L,Hardy D,Cokelaer T,Pineau P,Lecuit M,Lledo PM,Changeux JP,Bourhy H
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunohistochemistry
Mon Aug 09 00:00:00 EDT 2021
VX-765 reduces neuroinflammation after spinal cord injury in mice.
Neural regeneration research
Chen J,Chen YQ,Shi YJ,Ding SQ,Shen L,Wang R,Wang QY,Zha C,Ding H,Hu JG,Lü HZ
PA5-29645 was used in Immunohistochemistry to suggest that VX-765 can reduce neuroinflammation and improve nerve function recovery after spinal cord injury by inhibiting caspase-1/interleukin-1β/interleukin-18.
Wed Sep 01 00:00:00 EDT 2021
Exposure to Microbial Metabolite Butyrate Prolongs the Survival Time and Changes the Growth Pattern of Human Papillomavirus 16 E6/E7-Immortalized Keratinocytes in Vivo.
The American journal of pathology
Li M,McGhee EM,Shinno L,Lee K,Lin YL
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunohistochemistry
Fri Oct 01 00:00:00 EDT 2021
Exposure to Microbial Metabolite Butyrate Prolongs the Survival Time and Changes the Growth Pattern of Human Papillomavirus 16 E6/E7-Immortalized Keratinocytes in Vivo.
The American journal of pathology
Li M,McGhee EM,Shinno L,Lee K,Lin YL
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunohistochemistry
Fri Oct 01 00:00:00 EDT 2021
Cholecystokinin Receptor Antagonist Improves Efficacy of Chemotherapy in Murine Models of Pancreatic Cancer by Altering the Tumor Microenvironment.
Cancers
Malchiodi ZX,Cao H,Gay MD,Safronenka A,Bansal S,Tucker RD,Weinberg BA,Cheema A,Shivapurkar N,Smith JP
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunohistochemistry
Thu Sep 30 00:00:00 EDT 2021
Inactivation of Interleukin-4 Receptor α Signaling in Myeloid Cells Protects Mice From Angiotensin II/High Salt-Induced Cardiovascular Dysfunction Through Suppression of Fibrotic Remodeling.
Journal of the American Heart Association
Song J,Frieler RA,Vigil TM,Ma J,Brombacher F,Goonewardena SN,Goldstein DR,Mortensen RM
PA5-29645 was used in Immunohistochemistry to conclude that inhibiting myeloid IL-4Rα signaling may be a potential strategy to prevent hypertensive cardiovascular diseases.
Tue Jul 06 00:00:00 EDT 2021
Inactivation of Interleukin-4 Receptor α Signaling in Myeloid Cells Protects Mice From Angiotensin II/High Salt-Induced Cardiovascular Dysfunction Through Suppression of Fibrotic Remodeling.
Journal of the American Heart Association
Song J,Frieler RA,Vigil TM,Ma J,Brombacher F,Goonewardena SN,Goldstein DR,Mortensen RM
PA5-29645 was used in Immunohistochemistry to conclude that inhibiting myeloid IL-4Rα signaling may be a potential strategy to prevent hypertensive cardiovascular diseases.
Tue Jul 06 00:00:00 EDT 2021
Vaccination with Polyclonal Antibody Stimulator (PAS) Prevents Pancreatic Carcinogenesis in the KRAS Mouse Model.
Cancer prevention research (Philadelphia, Pa.)
Smith JP,Cao H,Chen W,Kallakury B,Phillips T,Sutton L,Cato A
PA5-29645 was used in Immunohistochemistry to show that the gastrointestinal peptide gastrin, which is only expressed in the fetal pancreas and not in the adult pancreas, is activated during pancreatic carcinogenesis where it stimulates growth in an autocrine fashion.
Fri Oct 01 00:00:00 EDT 2021
Zoledronate alters natural progression of tissue-engineered vascular grafts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chang YC,Li J,Mirhaidari G,Zbinden J,Barker J,Blum K,Reinhardt J,Best C,Kelly J,Shoji T,Yi T,Breuer C
PA5-29645 was used in Immunohistochemistry to examine the effect of zoledronate on tissue-engineered vascular grafts (TEVGs) neotissue formation and its potential application for mitigating TEVG stenosis.
Fri Oct 01 00:00:00 EDT 2021
Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis.
Molecular therapy : the journal of the American Society of Gene Therapy
Xu Y,Xu Y,Zhu Y,Sun H,Juguilon C,Li F,Fan D,Yin L,Zhang Y
PA5-29645 was used in Western Blotting to investigate the mechanism of microRNA-34a (miR-34a) that regulating macrophage cholesterol efflux and reverse cholesterol transport.
Wed Jan 08 00:00:00 EST 2020
Partial Inhibition of Glycolysis Reduces Atherogenesis Independent of Intraplaque Neovascularization in Mice.
Arteriosclerosis, thrombosis, and vascular biology
Perrotta P,Van der Veken B,Van Der Veken P,Pintelon I,Roosens L,Adriaenssens E,Timmerman V,Guns PJ,De Meyer GRY,Martinet W
PA5-29645 was used in Immunohistochemistry to demonstrate the inhibitiition of intraplaque neovascularization with 3PO.
Fri May 01 00:00:00 EDT 2020
CISD2 Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia.
Frontiers in aging neuroscience
Lin MS
PA5-29645 was used in Western Blotting to investigate whether CISD2 attenuation influences anti-inflammatory effects and M1-M2 polarization in microglia.
Sat Oct 03 00:00:00 EDT 2020
CISD2 Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia.
Frontiers in aging neuroscience
Lin MS
PA5-29645 was used in Western Blotting to investigate whether CISD2 attenuation influences anti-inflammatory effects and M1-M2 polarization in microglia.
Sat Oct 03 00:00:00 EDT 2020
Ultrashort Wave Combined with Human Umbilical Cord Mesenchymal Stem Cell (HUC-MSC) Transplantation Inhibits NLRP3 Inflammasome and Improves Spinal Cord Injury via MK2/TTP Signalling Pathway.
BioMed research international
Na L,Wang S,Liu T,Zhang L
PA5-29645 was used in Immunohistochemistry-immunofluorescence to investigate the curative effects of HUC-MSCs and USW on spinal cord injury and the influence MK2/TTP on the inflammatory microenvironment and its effects on spinal cord injury.
Tue Jun 08 00:00:00 EDT 2021
Fruquintinib inhibits VEGF/VEGFR2 axis of choroidal endothelial cells and M1-type macrophages to protect against mouse laser-induced choroidal neovascularization.
Cell death & disease
Liu X,Guo A,Tu Y,Li W,Li L,Liu W,Ju Y,Zhou Y,Sang A,Zhu M
PA5-29645 was used in Western Blotting to study the molecular mechanism.
Fri Nov 27 00:00:00 EST 2020
Fruquintinib inhibits VEGF/VEGFR2 axis of choroidal endothelial cells and M1-type macrophages to protect against mouse laser-induced choroidal neovascularization.
Cell death & disease
Liu X,Guo A,Tu Y,Li W,Li L,Liu W,Ju Y,Zhou Y,Sang A,Zhu M
PA5-29645 was used in Western Blotting to study the molecular mechanism.
Fri Nov 27 00:00:00 EST 2020
Knockdown of Leptin Receptor Affects Macrophage Phenotype in the Tumor Microenvironment Inhibiting Breast Cancer Growth and Progression.
Cancers
Gelsomino L,Naimo GD,Malivindi R,Augimeri G,Panza S,Giordano C,Barone I,Bonofiglio D,Mauro L,Catalano S,Andò S
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunohistochemistry
Mon Jul 27 00:00:00 EDT 2020
Knockdown of Leptin Receptor Affects Macrophage Phenotype in the Tumor Microenvironment Inhibiting Breast Cancer Growth and Progression.
Cancers
Gelsomino L,Naimo GD,Malivindi R,Augimeri G,Panza S,Giordano C,Barone I,Bonofiglio D,Mauro L,Catalano S,Andò S
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunohistochemistry
Mon Jul 27 00:00:00 EDT 2020
Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype.
International journal of molecular sciences
Pavlović N,Kopsida M,Gerwins P,Heindryckx F
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunocytochemistry
Sat Oct 31 00:00:00 EDT 2020
CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment.
Journal of neuroinflammation
Chen YQ,Wang SN,Shi YJ,Chen J,Ding SQ,Tang J,Shen L,Wang R,Ding H,Hu JG,Lü HZ
PA5-29645 was used in Immunohistochemistry (Frozen) to study the effect of CRID3 on the local microenvironment and the possible role in neuroprotection following spinal cord injury.
Sat Aug 29 00:00:00 EDT 2020
Vaccine against gastrin, a polyclonal antibody stimulator, decreases pancreatic cancer metastases.
American journal of physiology. Gastrointestinal and liver physiology
Osborne N,Sundseth R,Gay MD,Cao H,Tucker RD,Nadella S,Wang S,Liu X,Kroemer A,Sutton L,Cato A,Smith JP
PA5-29645 was used in Immunohistochemistry to investigate the effects of lone and combined treatment of polyclonal antibody stimulator, an anti-gastrin cancer vaccine, on pancreatic cancer growth, metastases, and the tumor microenvironment.
Fri Nov 01 00:00:00 EDT 2019
Colony‑stimulating factor 1 receptor inhibition blocks macrophage infiltration and endometrial cancer cell proliferation.
Molecular medicine reports
Hua F,Tian Y,Gao Y,Li C,Liu X
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunocytochemistry
Mon Apr 01 00:00:00 EDT 2019
Sub-clinical dose of bone morphogenetic protein-2 does not precipitate rampant, sustained inflammatory response in bone wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Grey ZJ,Howie RN,Durham EL,Hall SR,Helke KL,Steed MB,LaRue AC,Muise-Helmericks RC,Cray JJ
PA5-29645 was used in Immunohistochemistry to suggest that rhBMP-2 delivered at a lower dose does not precipitate rampant inflammation. Thus, an assessment of dosing for rhBMP-2 therapies may lead to better healing outcomes and less surgical failure.
Mon Jul 01 00:00:00 EDT 2019
Diet Supplementation in ω3 Polyunsaturated Fatty Acid Favors an Anti-Inflammatory Basal Environment in Mouse Adipose Tissue.
Nutrients
Colson C,Ghandour RA,Dufies O,Rekima S,Loubat A,Munro P,Boyer L,Pisani DF
PA5-29645 was used in Immunohistochemistry on paraffin embedded tissues to demonstrate that an ω3-enriched diet, in non-obesogenic non-inflammatory conditions, induced synthesis of oxylipins which were involved in an anti-inflammatory response as well as enhancement of the M2 macrophage molecular signature, without affecting inflammatory cytokine secretion.
Wed Feb 20 00:00:00 EST 2019
Formyl Peptide Receptor 2 Activation Ameliorates Dermal Fibrosis and Inflammation in Bleomycin-Induced Scleroderma.
Frontiers in immunology
Park GT,Kwon YW,Lee TW,Kwon SG,Ko HC,Kim MB,Kim JH
PA5-29645 was used in Immunohistochemistry to investigate the effects of Fpr2 activation in the treatment of scleroderma fibrosis.
Mon Nov 09 00:00:00 EST 2020
Umbilical cord-derived mesenchymal stem cell extracts reduce colitis in mice by re-polarizing intestinal macrophages.
Scientific reports
Song JY,Kang HJ,Hong JS,Kim CJ,Shim JY,Lee CW,Choi J
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunohistochemistry
Fri Aug 25 00:00:00 EDT 2017
Umbilical cord-derived mesenchymal stem cell extracts reduce colitis in mice by re-polarizing intestinal macrophages.
Scientific reports
Song JY,Kang HJ,Hong JS,Kim CJ,Shim JY,Lee CW,Choi J
Published figure using Arginase 1 polyclonal antibody (Product # PA5-29645) in Immunohistochemistry
Fri Aug 25 00:00:00 EDT 2017
