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Aspartate Aminotransferase, Cytoplasmic Antibody (MA5-36093) in IHC (P)
Immunohistochemical analysis of Aspartate Aminotransferase, Cytoplasmic in paraffin-embedded human colon carcinoma tissue using a monoclonal antibody (Product #MA5-36093). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with th... View More
产品信息
MA5-36093
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
A2D7
抗原
Recombinant protein within Human GOT1 aa 16-211
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 0.2% BSA, 50% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2890416
靶标信息
GOT1 is a glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aspartate aminotransferase 1; Aspartate aminotransferase, cytoplasmic; aspartate transaminase 1; cAspAT; cCAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cytosolic aspartate aminotransferase; Glutamate oxaloacetate transaminase 1; glutamate oxaloacetate transaminase 1, soluble; glutamic-oxaloacetic transaminase 1, soluble; growth-inhibiting protein 18; testis secretory sperm-binding protein Li 196a; Transaminase A
基因别名: AI789014; Aspat; AST1; ASTQTL1; cAspAT; cCAT; Gaspat; GIG18; Got-1; GOT1
UniProt ID: (Human) P17174, (Rat) P13221, (Mouse) P05201
Entrez Gene ID: (Human) 2805, (Rat) 24401, (Mouse) 14718
L-aspartate:2-oxoglutarate aminotransferase activity
phosphatidylserine decarboxylase activity
pyridoxal phosphate binding
carboxylic acid binding
identical protein binding
L-cysteine:2-oxoglutarate aminotransferase activity
L-phenylalanine:2-oxoglutarate aminotransferase activity
catalytic activity
transaminase activity
transferase activity
transaminase
gluconeogenesis
2-oxoglutarate metabolic process
oxaloacetate metabolic process
glycerol biosynthetic process
aspartate metabolic process
aspartate biosynthetic process
aspartate catabolic process
glutamate metabolic process
Notch signaling pathway
cellular amino acid biosynthetic process
glutamate catabolic process to aspartate
glutamate catabolic process to 2-oxoglutarate
cellular response to insulin stimulus
response to glucocorticoid
fatty acid homeostasis
dicarboxylic acid metabolic process
cellular amino acid metabolic process
biosynthetic process
