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产品信息
ACRD6M-BIOTIN
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 300-378 mouse Atypical chemokine receptor 2 protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Atypical chemokine receptor 2; C-C chemokine receptor D6; CC-chemokine-binding receptor JAB61; CCR10-related receptor; chemokine binding protein 2; chemokine decoy receptor D6; Chemokine-binding protein 2; Chemokine-binding protein D6; D6 beta-chemokine receptor
基因别名: Ackr2; AI464239; Ccbp2; CCR10; CCR9; Cmkbr9; D6
UniProt ID: (Mouse) O08707
Entrez Gene ID: (Mouse) 59289, (Rat) 140473
