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Immunogen sequence: LLPEERLRNL FSYDGIWLFP KNQCKCEANK EQGGYNFQDA YGQSDLPAVK ARRQAEFEHF QRREGLPRPL PLLVQPNLPF GYPVHGVEVM PLHTVPIPGL QFEGPDA
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 25%.
B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an alpha-2,3-linked sialic acid. B4GALNT2 also catalyzes the last step in the biosynthesis of the Cad antigen (Montiel et al., 2003 [PubMed 12678917]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: beta 1,4 N-acetylgalactosaminyltransferase/betal,4 GalNAcT/Sda-GalNAcT; Beta-1,4 N-acetylgalactosaminyltransferase 2; beta-1,4-N-acetyl-galactosaminyl transferase 2; beta-4-N-acetylgalactosaminyltransferase; Sd(a) beta-1,4-GalNAc transferase; sda beta-1,4-GalNAc transferase; UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase; UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase
基因别名: B4GALNT2; B4GALT; GALGT2
UniProt ID: (Human) Q8NHY0
Entrez Gene ID: (Human) 124872