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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKKKTRRRST RSEELTRSEE LTLSEEATWS EEATQSEEAT QGEEMNRSQE VTRDEESTRS EEVTREEMAA AGLTVTVTHS NEKHDLHVTS QQGSSEPVVQ DLAQVVEEVI GVPQSFQKLI FKGKSLKEME TPLSALGIQD GCRVMLIGKK NSPQEEVELK KLKHLEKSVE KIADQLEELN KELTGIQQGF LPKDLQAEAL CKLDRRVKAT IEQFMKILEE IDTLILPENF KDSRLKRKGL VKKVQAFLAE CDTVEQNICQ ETERLQSTNF ALAE
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BAG family molecular chaperone regulator 1; BAG-1; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
基因别名: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933
Entrez Gene ID: (Human) 573