Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-120565
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 97-295 of human BAZ2A (NP_038477.2).
偶联物
形式
Liquid
浓度
2.03 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914137
产品详细信息
Positive test controls include: K-562, NIH/3T3.
Immunogen sequence: QYPSANPGSN LKDPPLLSQF SGGQYPLNGI LGGSRQPSSP SHNTNLRAGS QEFWANGTQS PMGLNFDSQE LYDSFPDQNF EVMPNGPPSF FTSPQTSPML GSSIQTFAPS QEVGSGIHPD EAAEKEMTSV VAENGTGLVG SLELEEEQPE LKMCGYNGSV PSVESLHQEV SVLVPDPTVS CLDDPSHLPD QLEDTPILS
靶标信息
TIP 5 is the large subunit of the nucleolar remodeling complex NoRC. NoRC causes the repression of ribosomal gene transcription. It was demonstrated that histone deacetylation is involved in this repression and that TIP5 is associated with the histone deacetylase HDAC1 and mediates the deacetylation of histones in the vicinity of the rDNA promoter. The interaction of TIP5 and HDAC1, which is necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Bromodomain adjacent to zinc finger domain protein 2A; bromodomain adjacent to zinc finger domain, 2A; hWALp3; Transcription termination factor I-interacting protein 5; TTF-I interacting peptide 5; TTF-I-interacting protein 5
基因别名: AA415431; BAZ2A; C030005G16Rik; C78388; KIAA0314; mKIAA0314; TIP5; WALp3
UniProt ID: (Human) Q9UIF9
Entrez Gene ID: (Human) 11176, (Rat) 304601, (Mouse) 116848
chromatin silencing at rDNA
DNA methylation
chromatin remodeling
transcription, DNA-templated
regulation of transcription, DNA-templated
histone deacetylation
histone H4-K20 methylation
histone H3-K9 methylation
heterochromatin assembly involved in chromatin silencing
histone H4 deacetylation
chromatin modification
