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产品信息
BS-6613R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human BCAT1, amino acids 321-386.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
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生物信息学
蛋白别名: BCAT(c); branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; Branched-chain-amino-acid aminotransferase, cytosolic; placental protein 18; Protein ECA39
基因别名: BCAT1; BCATC; BCT1; ECA39; MECA39; PNAS121; PP18
UniProt ID: (Human) P54687, (Mouse) P24288, (Rat) P54690
Entrez Gene ID: (Human) 586, (Mouse) 12035, (Rat) 29592
branched-chain-amino-acid transaminase activity
pyridoxal phosphate binding
identical protein binding
L-leucine transaminase activity
L-valine transaminase activity
L-isoleucine transaminase activity
catalytic activity
transaminase activity
transferase activity
transaminase
transferase
metabolite interconversion enzyme
G1/S transition of mitotic cell cycle
aspartate biosynthetic process
cell proliferation
branched-chain amino acid biosynthetic process
branched-chain amino acid catabolic process
leucine biosynthetic process
valine biosynthetic process
metabolic process
cellular amino acid biosynthetic process
branched-chain amino acid metabolic process
mitotic G1 DNA damage checkpoint
cellular response to UV
biological_process
