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产品信息
TA504360
产品规格
种属反应
Dog,
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI3F5
抗原
Full length human recombinant protein of human BCAT1 produced in HEK293T cell.
偶联物
形式
Liquid
浓度
0.78 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCAT(c); branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; Branched-chain-amino-acid aminotransferase, cytosolic; placental protein 18; Protein ECA39
基因别名: BCAT1; BCATC; BCT1; ECA39; MECA39; PNAS121; PP18
UniProt ID: (Human) P54687, (Mouse) P24288
Entrez Gene ID: (Human) 586, (Dog) 486633, (Mouse) 12035
branched-chain-amino-acid transaminase activity
pyridoxal phosphate binding
identical protein binding
L-leucine transaminase activity
L-valine transaminase activity
L-isoleucine transaminase activity
catalytic activity
transaminase activity
transferase activity
transaminase
transferase
metabolite interconversion enzyme
G1/S transition of mitotic cell cycle
aspartate biosynthetic process
cell proliferation
branched-chain amino acid biosynthetic process
branched-chain amino acid catabolic process
leucine biosynthetic process
valine biosynthetic process
metabolic process
cellular amino acid biosynthetic process
branched-chain amino acid metabolic process
mitotic G1 DNA damage checkpoint
cellular response to UV
