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Immunogen sequence: SLYSGLSTPP ASYSMYSHLP VSSLLFSDEE FRDVRMPVAN PFPKERALPC DSARPVPGEY SRPTLEVSPN VCHSNIYSPK ETIPEEARSD MHYSVAEGLK PAAPSARNAP YFPCDKASKE EERPSSEDEI ALHFEPPNAP LNRKGLVSPQ SPQKSDCQPN SPTESCSSKN ACILQASGSP PAKSPTDPKA CNWKKYKFIV LNSLNQNAKP EGPEQAELGR LSPRAYTAPP ACQPPMEPEN LDLQSPTKLS ASGEDSTIPQ ASRLNNIVNR SMTGSPRSSS ESHSPLYMHP PKCTSCGSQS PQHAEMCLHT AGPTFPEEMG ETQSEYSDSS CENGAFFCNE CDCRFSEEAS
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B-cell lymphoma 5 protein; B-cell lymphoma 5 protein (BCL5); B-cell lymphoma 6 protein; B-cell lymphoma 6 protein transcript; BCL-5; BCL-6; cys his2 zinc finger transcription factor; cys-his2 zinc finger transcription factor; LAZ-3 protein; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); lymphoma-associated zinc finger gene on chromosome 3; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc finger protein 51; Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S
基因别名: BCL5; BCL6; BCL6A; LAZ3; ZBTB27; ZNF51
UniProt ID: (Human) P41182
Entrez Gene ID: (Human) 604