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Sequence of this protein is as follows: MGLVSSKKPD KEKPIKEKDK GQWSPLKVSA QDKDAPPLPP LVVFNHLTPP PPDEHLDEDK HFVVALYDYT AMNDRDLQML KGEKLQVLKG
B-lymphoid tyrosine kinase (BLK) is a non-receptor tyrosine kinase that belongs to the Src family of kinases. BLK plays an important role in B-cell activation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
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蛋白别名: B lymphocyte kinase; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase; MGC10442; p55-Blk; Tyrosine-protein kinase Blk
基因别名: BLK; MODY11
UniProt ID: (Human) P51451, (Mouse) P16277
Entrez Gene ID: (Human) 640, (Mouse) 12143, (Rat) 364403