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产品信息
TA807459
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI6F3
抗原
Full length human recombinant protein of human BMF ( NP_001003940) produced in E.coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bcl-2-modifying factor; FLJ00065
基因别名: BMF
UniProt ID: (Human) Q96LC9
Entrez Gene ID: (Human) 90427
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
positive regulation of protein homooligomerization
positive regulation of apoptotic process
anoikis
positive regulation of release of cytochrome c from mitochondria
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
positive regulation of intrinsic apoptotic signaling pathway
