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The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BMP; BMP-8; BMP-8A; BMP-8B; Bone morphogenetic protein; bone morphogenetic protein 8 (osteogenic protein 2); Bone morphogenetic protein 8A; Bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP-2; Osteogenic protein 2
基因别名: Bmp-8; Bmp7r1; BMP8; BMP8A; BMP8B; OP-2; OP2; Op3
UniProt ID: (Human) Q7Z5Y6, (Human) P34820, (Mouse) P34821, (Mouse) P55105
Entrez Gene ID: (Human) 353500, (Human) 656, (Mouse) 12163, (Rat) 680931, (Mouse) 12164, (Rat) 679119