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Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B-cell-specific coactivator OBF-1; BOB-1; OCA-B; OCT-binding factor 1; POU domain class 2-associating factor 1; POU domain, class 2, associating factor 1
基因别名: BOB1; OBF-1; OBF1; OCAB; POU2AF1
UniProt ID: (Human) Q16633
Entrez Gene ID: (Human) 5450