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产品信息
PA5-56680
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2638649
产品详细信息
Immunogen sequence: QQQEELEAEH GTGDKPAAPR ERTTRLGPRM PQDGSDDEDE EWPTLEKAAT MTAAGHHAEV VVDPEDERAI EMFMNKNPPA R
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 83%.
靶标信息
Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.
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生物信息学
蛋白别名: by the ribosomal protein s6 gene, drosophila, homolog-like; Bystin; bystin-like
基因别名: BYSL; BYSTIN; ENP1
UniProt ID: (Human) Q13895
Entrez Gene ID: (Human) 705
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
trophectodermal cell differentiation
rRNA processing
cell adhesion
brain development
female pregnancy
cell proliferation
neuron differentiation
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to growth factor stimulus
cellular response to organic cyclic compound
