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产品信息
A16707
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
D24A9
抗原
synthetic peptide corresponding to residues surrounding Pro102 of human Bad.
偶联物
形式
Liquid
保存条件
-20°C
运输条件
Ambient
靶标信息
The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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