NeoBiotechnologies

Bcl-6 (Follicular Lymphoma Marker) Recombinant Rabbit Monoclonal Antibody (BCL6/9222R)

Bcl-6 (Follicular Lymphoma Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Bcl-6 (Follicular Lymphoma Marker) Antibody (604-RBM32-P1) in IHC (P)

Formalin-fixed, paraffin-embedded human tonsil stained with BCL-6 Rabbit Recombinant Monoclonal Antibody (BCL6/9222R). Inset: PBS instead of primary antibody; secondary only negative control.

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产品信息

604-RBM32-P1

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG, kappa

Expression System

CHO cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

BCL6/9222R

抗原

Recombinant fragment (aa1-400) of human BCL6 protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Positive Control:Raji or Ramos cells. Human tonsil or Hodgkin s lymphoma.

Cellular Location: Nucleus.

靶标信息

Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: B-cell lymphoma 5 protein; B-cell lymphoma 5 protein (BCL5); B-cell lymphoma 6 protein; B-cell lymphoma 6 protein transcript; BCL-5; BCL-6; cys his2 zinc finger transcription factor; cys-his2 zinc finger transcription factor; LAZ-3 protein; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); lymphoma-associated zinc finger gene on chromosome 3; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc finger protein 51; Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S

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基因别名: BCL5; BCL6; BCL6A; LAZ3; ZBTB27; ZNF51

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UniProt ID: (Human) P41182

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Entrez Gene ID: (Human) 604

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功能

RNA polymerase II regulatory region sequence-specific DNA binding intronic transcription regulatory region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding chromatin DNA binding sequence-specific DNA binding metal ion binding C2H2 zinc finger transcription factor

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