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Positive Control: Human blood plasma, HepG2, LOVO, human liver tissue, human colon cancer tissue, human skin tissue, human prostate tissue.
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Acylcholine acylhydrolase; BtChE; Butyrylcholine esterase; Choline esterase II; Cholinesterase; cholinesterase (serum) 2; cholinesterase 1; EC 3.1.1.8; Pseudocholinesterase
基因别名: BCHE; CHE1; CHE2; E1
UniProt ID: (Human) P06276
Entrez Gene ID: (Human) 590