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C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of ~104 kDa. Serum concentration has been determined to 180 µg/mL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C1 esterase inhibitor; C1 Inh; C1-inhibiting factor; complement component 1 inhibitor; esterase inhibitor; IC1; Plasma protease C1 inhibitor; serine/cysteine proteinase inhibitor clade G member 1; Serpin G1; serpin peptidase inhibitor clade G member 1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
基因别名: C1IN; C1INH; C1NH; HAE1; HAE2; SERPING1
UniProt ID: (Human) P05155
Entrez Gene ID: (Human) 710