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产品信息
PA5-65640
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2663855
产品详细信息
Immunogen sequence: HTAFTKHSEEL GTEEGEVEEM DTLDPQTGLF YRSALTQSQS AKQQKLSQPP LEQTQLQVKT LQCFQTKQKQ TIHLQADQLQ HKLPQMPQLS IRHQKLTPLQ QEQAQPKPDV QHTQHPMVAK DRQLPTLMAQ PPQTVVQVLA VKTTQQL
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
靶标信息
EMSY is a regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.
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生物信息学
蛋白别名: BRCA2-interacting transcriptional repressor EMSY; EMSY BRCA2-interacting transcriptional repressor; EMSY protein; EMSY, BRCA2-interacting transcriptional repressor; FLJ90741; protein EMSY
基因别名: C11orf30; EMSY; GL002
UniProt ID: (Human) Q4G109
Entrez Gene ID: (Human) 56946
