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C1GALT1C1 Antibody (PA5-121119) in WB
Western blot analysis of C1GALT1C1 in extracts of various cell lines. Samples were incubated with C1GALT1C1 Polyclonal antibody (Product # PA5-121119) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-121119
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 30-190 of human C1GALT1C1 (NP_689905.1).
偶联物
形式
Liquid
浓度
1.25 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914691
产品详细信息
Positive test controls include: HeLa, Mouse liver, Mouse kidney. The target is usually found in the following locations: Membrane, Single-pass type II membrane protein.
Immunogen sequence: IGHGNRMHHH EHHHLQAPNK EDILKISEDE RMELSKSFRV YCIILVKPKD VSLWAAVKET WTKHCDKAEF FSSENVKVFE SINMDTNDMW LMMRKAYKYA FDKYRDQYNW FFLARPTTFA IIENLKYFLL KKDPSQPFYL GHTIKSGDLE YVGMEGGIVL S
靶标信息
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: beta 1,3-galactosyltransferase 2; beta1,3-galactosyltransferase 2; C1Gal-T2; C1GALT1-specific chaperone 1; C38H2-L1; C38H2-like protein 1; Core 1 beta1,3-galactosyltransferase 2; core 1 beta3-Gal-T2; Core 1 beta3-galactosyltransferase-specific molecular chaperone; core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 2; mC1Gal-T2
基因别名: 1500002I11Rik; AB030184; C1GALT1C1; C1GALT2; C38H2-L1; C81205; COSMC; HSPC067; MST143; MSTP143; RGD1311230; TNPS; UNQ273/PRO310
UniProt ID: (Human) Q96EU7, (Mouse) Q9JMG2, (Rat) Q499P3
Entrez Gene ID: (Human) 29071, (Mouse) 59048, (Rat) 302499
