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C1QBP Antibody (80490-1-RR100UL) in ICC/IF
Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using C1QBP antibody (Product # 80490-1-RR100UL), Clone: 3K20 ) at dilution of 1:500 and CoraLite 488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CoraLite 594 Beta Actin antibody (CL594-66009, Clone: 2D4H5, red).
产品信息
80490-1-RR100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
proprietary
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3K20
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
靶标信息
Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1qBP; Complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; GC1q-R protein; Glycoprotein gC1qBP; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; p33; RPA; SF2AP32; splicing factor SF2-associated protein
基因别名: AA407365; AA986492; C1QBP; D11Wsu182e; gC1Q-R; GC1QBP; gC1qR; HABP1; P32; SF2P32
UniProt ID: (Human) Q07021, (Rat) O35796
Entrez Gene ID: (Human) 708, (Rat) 29681, (Mouse) 12261
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
mRNA processing
apoptotic process
immune response
complement activation, classical pathway
RNA splicing
phosphatidylinositol 3-kinase signaling
regulation of complement activation
negative regulation of interferon-gamma production
negative regulation of interleukin-12 production
negative regulation of MDA-5 signaling pathway
negative regulation of RIG-I signaling pathway
mature ribosome assembly
positive regulation of apoptotic process
innate immune response
positive regulation of cell adhesion
negative regulation of mRNA splicing, via spliceosome
negative regulation of defense response to virus
positive regulation of protein kinase B signaling
positive regulation of mitochondrial translation
positive regulation of neutrophil chemotaxis
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of trophoblast cell migration
positive regulation of dendritic cell chemotaxis
immune system process
regulation of transcription, DNA-templated
ribosome biogenesis
blood coagulation, intrinsic pathway
viral process
