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Invitrogen
C2orf33 Polyclonal Antibody
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 5
C2orf33 Antibody (PA5-52765) in ICC/IF
Immunofluorescence analysis of C2orf33 was performed using HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with C2orf33 Rabbit Polyclonal Antibody (Product # PA5-52765) at 5µg/mL dilution in 0.1% BSA and incubated overnight at 4 degree and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at a dilution ... View More
产品信息
PA5-52765
产品规格
种属反应
Human
已发表种属
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639010
产品详细信息
Immunogen sequence: RFQAPISAPE YTVTPSPQQA RVCPPHMLPE DGANLSSARG ILSLIQSSTR RAYQQILDVL DENRRPVLRG GSAAATSNPH HDNVRYGISN IDTTIEGTSD DLTVVDAASL RRQIIKLNRR LQLLEEENKE RAKR
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 83%.
靶标信息
Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. [Uniprot]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Mitochondrial fission factor
基因别名: AD030; AD033; C2orf33; GL004; MFF
UniProt ID: (Human) Q9BVZ1
Entrez Gene ID: (Human) 56947
mitochondrial fission
release of cytochrome c from mitochondria
protein targeting to mitochondrion
mitochondrial fusion
regulation of mitochondrion organization
peroxisome fission
mitochondrial fragmentation involved in apoptotic process
protein homooligomerization
mitochondrion morphogenesis
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
positive regulation of protein targeting to membrane
regulation of peroxisome organization
