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1 µg/mL of MA5-45587 was sufficient for detection of TARP Gamma2/4/8 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.|Detects approximately 35-55kDa. Does not cross-react with TARPGamma3.
This antibody was formerly sold as clone S245-36.
Voltage-dependent calcium channel gamma-2 subunit, TARPGamma2 or Stargazin is encoded by the gene CACNG2 and is the transmembrane gamma subunit of the L-type calcium channel. Stargazin is in involved in regulation and trafficking of the ligand gated ion channel AMPA receptors. It is thought to play a role in learning and memory. Diseases associated with this gene include forms of deafness, Mental Retardation and childhood absnce epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: calcium channel, voltage-dependent, gamma subunit 2; calcium channel, voltage-dependent, gamma subunit 4; calcium channel, voltage-dependent, gamma subunit 8; Neuronal voltage-gated calcium channel gamma-2 subunit; Neuronal voltage-gated calcium channel gamma-4 subunit; Neuronal voltage-gated calcium channel gamma-8 subunit; Stargazin; TARP gamma 2; TARP gamma 8; TARP gamma-2; TARP gamma-4; TARP gamma-8; Transmembrane AMPAR regulatory protein gamma-2; Transmembrane AMPAR regulatory protein gamma-4; Transmembrane AMPAR regulatory protein gamma-8; Voltage-dependent calcium channel gamma-2 subunit; Voltage-dependent calcium channel gamma-4 subunit; Voltage-dependent calcium channel gamma-8 subunit
基因别名: AI413107; AW060990; AW491861; B230105C07Rik; B930041E13Rik; CACNG2; CACNG4; CACNG6; CACNG8; Ipr328; mir-935; MRD10; stargazer; stargazin; Stg; wag; waggler
UniProt ID: (Human) Q9Y698, (Human) Q9UBN1, (Human) Q8WXS5, (Rat) Q71RJ2, (Mouse) O88602, (Rat) Q8VHW9, (Mouse) Q9JJV4, (Rat) Q8VHW5
Entrez Gene ID: (Human) 10369, (Human) 27092, (Human) 59283, (Rat) 84347, (Mouse) 12300, (Rat) 140725, (Mouse) 54377, (Rat) 140729, (Mouse) 81905
分子生物学功能:
voltage-gated ion channel