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CAP1 Antibody (PA5-89912) in WB
Western blot analysis of CAP1 in extracts of various cell lines. Samples were incubated with CAP1 Polyclonal antibody (Product # PA5-89912) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-89912
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CAP1 (NP_0063581)
偶联物
形式
Liquid
浓度
0.44 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805839
产品详细信息
Immunogen sequence: MADMQNLVER LERAVGRLEA VSHTSDMHRG YADSPSKAGA APYVQAFDSL LAGPVAEYLK ISKEIGGDVQ KHAEMVHTGL KLERALLVTA SQCQQPAENK; Positive Samples: HeLa, 293T, A-431, HepG2, Rat thymus, Mouse thymus; Cellular Location: Cell membrane, Peripheral membrane protein
靶标信息
Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene. This gene is mapped to 1p34. 2. The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. And the human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adenylyl cyclase-associated CAP protein, yeast homolog 1; Adenylyl cyclase-associated protein 1; CAP 1; CAP, adenylate cyclase-associated protein 1; cyclase-associated protein homologue; RP11-115D7.1; testis secretory sperm-binding protein Li 218p
基因别名: CAP; CAP1; CAP1-PEN; Mch1
UniProt ID: (Human) Q01518, (Rat) Q08163, (Mouse) P40124
Entrez Gene ID: (Human) 10487, (Rat) 64185, (Mouse) 12331
cell morphogenesis
ameboidal-type cell migration
receptor-mediated endocytosis
establishment or maintenance of cell polarity
signal transduction
activation of adenylate cyclase activity
actin polymerization or depolymerization
biological_process
actin cytoskeleton organization
cytoskeleton organization
