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Immunogen sequence: SQCNLYMAAR KAVRKRPNQA LLENIALYLT HMLKIFGAVE EDSSLGFPVG GPGTSLSLEA TVMPYLQVLS EFREGVRKIA REQKVPEILQ LSDALRDNIL PELGVRFEDH EGLPTVVKLV DRNTLLKERE EKRRVE
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
Binds to an epitope located within the peptide sequence EDSSLGFPVG as determined by overlapping synthetic peptides.
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CysRS; cysteine translase; cysteine tRNA ligase 1, cytoplasmic; Cysteine--tRNA ligase, cytoplasmic; Cysteinyl-tRNA synthetase
基因别名: CARS; CARS1; CYSRS; MGC:11246
UniProt ID: (Human) P49589
Entrez Gene ID: (Human) 833