Proteintech

CBS Monoclonal Antibody (1E4F10)

1 篇参考文献

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抗体检测数据 (3)

CBS Antibody in Immunohistochemistry (Paraffin) (IHC (P))

CBS Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CBS Antibody (67861-1-IG) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 67861-1-Ig (CBS antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CBS Antibody in Immunohistochemistry (Paraffin) (IHC (P))

CBS Antibody in Immunohistochemistry (Paraffin) (IHC (P))

CBS Antibody in Western Blot (WB)

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CBS Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 67861-1-Ig (CBS antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CBS Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 67861-1-Ig (CBS antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CBS Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 67861-1-Ig (CBS antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

产品信息

67861-1-IG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:10,000

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:1,000

-

产品规格

种属反应

Human, Rat

已发表种属

Not Applicable

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

1E4F10

抗原

CBS Fusion Protein Ag7008

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1000 µg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

产品详细信息

Aliquoting is unnecessary for -20°C storage.

靶标信息

Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Du J,Wang P,Gou Q,Jin S,Xue H,Li D,Tian D,Sun J,Zhang X,Teng X,Wu Y

Wed Jun 01 00:00:00 EDT 2022

生物信息学

蛋白别名: Beta-thionase; Cystathionine beta-synthase; cystathionine-beta-synthase; Hemoprotein H-450; methylcysteine synthase; Serine sulfhydrase

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基因别名: CBS; HIP4

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UniProt ID: (Human) P35520, (Rat) P32232

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Entrez Gene ID: (Human) 875, (Rat) 24250

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cystathionine beta-synthase activity cysteine synthase activity protein binding oxygen binding enzyme binding heme binding pyridoxal phosphate binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity metal ion binding nitrite reductase (NO-forming) activity carbon monoxide binding nitric oxide binding modified amino acid binding S-adenosyl-L-methionine binding lyase metabolite interconversion enzyme

参与通路

cysteine biosynthetic process from serine L-serine metabolic process L-serine catabolic process cellular amino acid biosynthetic process cysteine biosynthetic process via cystathionine cysteine biosynthetic process transsulfuration L-cysteine catabolic process DNA protection homocysteine catabolic process homocysteine metabolic process oxidation-reduction process hydrogen sulfide biosynthetic process endochondral ossification blood vessel remodeling superoxide metabolic process cerebellum morphogenesis regulation of cGMP metabolic process response to nutrient levels negative regulation of apoptotic process regulation of JUN kinase activity regulation of blood vessel size response to folic acid maternal process involved in female pregnancy cartilage development involved in endochondral bone morphogenesis cellular response to hypoxia