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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
CCDC22 is a recently identified coiled-coil domain-containing protein that has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. In rat, CCDC22 has been observed to localize in multiple regions of the brain, including the prefrontal and somatosensory cortex, dentate gyrus and thalamus, and in the ipsilateral motor neurons of the spinal cord after sciatic nerve transection suggesting that it may play a role in neuronal injury response. The human CCDC22 gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability (XLID).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ccdc22 {ECO:0000250|UniProtKB:O60826}; Coiled-coil domain-containing protein 22; coiled-coil domain-containing protein 22 {ECO:0000250|UniProtKB:O60826}
基因别名: AI481216; CCDC22; CXorf37; DXImx40e; JM1; Ppp1r3f; RGD1560910; RTSC2; Sfc22
UniProt ID: (Human) O60826, (Mouse) Q9JIG7, (Rat) P86182
Entrez Gene ID: (Human) 28952, (Mouse) 54638, (Rat) 317381