Search Thermo Fisher Scientific
图: 1 / 3
AA Sequence of recombinant protein: SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine Exodus-2 (CCL21). Anti-Murine Exodus-2 (CCL21)-specific antibody was purified by affinity chromatography employing an immobilized Murine Exodus-2 (CCL21) matrix.
Sandwich ELISA: To detect Murine Exodus-2 (CCL21) by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine Exodus-2 (CCL21) (500-P114Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine Exodus-2 (CCL21).
Western Blot: To detect Murine Exodus-2 (CCL21) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine Exodus-2 (CCL21) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 6 Ckine; 6Ckine; beta chemokine exodus-2; Beta-chemokine exodus-2; C-C motif chemokine 21a; C-C motif chemokine 21b; C-C motif chemokine 21c; CC chemokine 6Ckine-ser; Ccl21-leu; CCL21-Ser; exodus-2; secondary lymphoid organ chemokine; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4
基因别名: 6CKBAC1; 6CKBAC2; 6Ckine; AI159701; ALP; AW987545; Ccl21a; Ccl21b; Ccl21c; CKb9; exodus-2; plt; Scya21; SCYA21a; Scya21b; Scya21c; SLC; TCA4
UniProt ID: (Mouse) P84444, (Mouse) P86792
Entrez Gene ID: (Mouse) 18829, (Mouse) 100042493, (Mouse) 65956