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AA Sequence of recombinant protein: APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA.
Preparation: Produced from sera of goats immunized with highly pure Recombinant Human LD78beta (CCL3L1). Anti-Human LD78beta (CCL3L1)-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA: To detect Human LD78beta by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.25-1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human LD78beta (500-P187G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human LD78beta.
Western Blot: To detect Human LD78beta by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human LD78beta is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
500-P187GBT-1MG will be provided as 2 x 500 µg
This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。