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CD123 Antibody (PA5-92099) in IHC (P)
Immunohistochemistry analysis of CD123 in paraffin-embedded mouse kidney. Samples were incubated with CD123 Polyclonal antibody (Product # PA5-92099) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-92099
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IL3RA (NP_0021741)
偶联物
Unconjugated
形式
Liquid
浓度
0.47 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2806378
产品详细信息
Immunogen sequence: MVLLWLTLLL IALPCLLQTK EDPNPPITNL RMKAKAQQLT WDLNRNVTDI ECVKDADYSM PAVNNSYCQF GAISLCEVTN YTVRVANPPF STWILFPENS; Positive Samples: A-549; Cellular Location: Membrane, Single-pass type I membrane protein
靶标信息
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD123; CD123 antigen; cytokine receptor-like protein CYRL; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; Interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha
基因别名: CD123; CDw123; Cyrl; hIL-3Ra; IL3R; IL3RA; IL3RAY; IL3RX; IL3RY; SUT-1
UniProt ID: (Human) P26951, (Mouse) P26952
Entrez Gene ID: (Human) 3563, (Rat) 246144, (Mouse) 16188
