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MA1-33449 detects CD13 from mouse samples.
CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alanyl aminopeptidase; Aminopeptidase M; Aminopeptidase N; aminopeptidase N/CD13; AP-M; AP-N; CD13; h AP-N; Membrane protein p161; Microsomal aminopeptidase
基因别名: Anpep; AP-M; AP-N; Apn; Cd13; Lap-1; Lap1; P150
UniProt ID: (Mouse) P97449
Entrez Gene ID: (Mouse) 16790