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CD138 Antibody (MA5-46733) in Flow
Flow cytometry analysis of CD138 (Syndecan-1) in RPMI8226 cells using CD138, APC Recombinant Monoclonal (Product # MA5-46733). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
产品信息
MA5-46733
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
017
抗原
Recombinant protein ecoding Human CD138 (Met1-Glu251).
偶联物
激发/发射光谱
651/660 nm
查看光谱
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein A
保存液
PBS with 0.5% BSA
内含物
0.03% Proclin 300
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2937805
产品详细信息
Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human CD138 (Syndecan-1) (Met1-Glu251) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze!
靶标信息
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; sCD138; soluble CD138; SYND1; syndecan proteoglycan 1; Syndecan-1; Syndecan1
基因别名: CD138; SDC; SDC1; SYND1; syndecan
UniProt ID: (Human) P18827
Entrez Gene ID: (Human) 6382
retinoid metabolic process
ureteric bud development
glycosaminoglycan biosynthetic process
glycosaminoglycan catabolic process
inflammatory response
response to toxic substance
cell migration
glycosaminoglycan metabolic process
wound healing
lipoprotein metabolic process
odontogenesis
response to hydrogen peroxide
myoblast development
response to glucocorticoid
response to cAMP
response to calcium ion
striated muscle cell development
Sertoli cell development
canonical Wnt signaling pathway
positive regulation of exosomal secretion
positive regulation of extracellular exosome assembly
