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CD147 Antibody (PA5-120474) in WB
Western blot analysis of CD147 in extracts of various cell lines. Samples were incubated with CD147 Polyclonal antibody (Product # PA5-120474) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
PA5-120474
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 286-385 of human CD147/CD147/BSG (NP_0017192)
偶联物
形式
Liquid
浓度
0.76 mg/mL
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914046
产品详细信息
Positive test controls include: HepG2, Mouse lung, Mouse brain, Rat lung. The target is usually found in the following locations: Cell membrane, Melanosome, Single-pass type I membrane protein.
Immunogen sequence: HIENLNMEAD PGQYRCNGTS SKGSDQAIIT LRVRSHLAAL WPFLGIVAEV LVLVTIIFIY EKRRKPEDVL DDDDAGSAPL KSSGQHQNDK GKNVRQRNSS
靶标信息
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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