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CD147 Antibody (MA5-50094) in ICC/IF
Immunocytochemistry analysis of HeLa cells with CD147 monoclonal antibody (Product # MA5-50094) at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG (H+L).
产品信息
MA5-50094
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
11F3
抗原
Recombinant Human CD147 protein
偶联物
形式
Liquid
浓度
0.65 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_3092489
靶标信息
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5F7; Basigin; CD147; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; HAb18G; Hepatoma-associated antigen; Leukocyte activation antigen M6; OK blood group antigen; TCSF; Tumor cell-derived collagenase stimulatory factor
基因别名: 5F7; BSG; CD147; EMMPRIN; OK; TCSF; UNQ6505/PRO21383
UniProt ID: (Human) P35613
Entrez Gene ID: (Human) 682
pyruvate metabolic process
cell surface receptor signaling pathway
embryo implantation
monocarboxylic acid transport
extracellular matrix disassembly
extracellular matrix organization
odontogenesis of dentin-containing tooth
response to peptide hormone
response to mercury ion
decidualization
leukocyte migration
response to cAMP
protein targeting to plasma membrane
cell-cell adhesion
