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Invitrogen
CD147 Recombinant Rabbit Monoclonal Antibody (23GB1460)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 4
CD147 Antibody (MA5-54218) in ICC/IF
Immunocytochemistry analysis of CD147 in HepG2 cells. Nuclei were stained blue with DAPI; CD147 recombinant monoclonal antibody (Product # MA5-54218) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
产品信息
MA5-54218
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB1460
抗原
A synthesized peptide derived from human CD147 (150-200AA).
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5A11/Basigin; 5F7; Basic immunoglobulin superfamily; Basigin; Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); CD147; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; Glycoprotein CE9; gp 42; HAb18G; Hepatoma-associated antigen; HT7 antigen; Leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK blood group antigen; OX-47 antigen; TCSF; Tumor cell-derived collagenase stimulatory factor
基因别名: 5A11; 5F7; AI115436; AI325119; basignin; BSG; CD147; CE9; EMMPRIN; HT-7; HT7; OK; Ox47R; TCSF; UNQ6505/PRO21383
UniProt ID: (Human) P35613, (Mouse) P18572, (Rat) P26453
Entrez Gene ID: (Human) 682, (Mouse) 12215, (Rat) 25246
pyruvate metabolic process
cell surface receptor signaling pathway
embryo implantation
monocarboxylic acid transport
extracellular matrix disassembly
extracellular matrix organization
odontogenesis of dentin-containing tooth
response to peptide hormone
response to mercury ion
decidualization
leukocyte migration
response to cAMP
protein targeting to plasma membrane
cell-cell adhesion
